A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock.
نویسندگان
چکیده
Visible-light triggered quinone trimethyl locks are reported as a general design for long-wavelength photoremovable protecting groups for alcohols and amines. Intramolecular photoreduction unmasks a reactive phenol that undergoes fast lactonization to release alcohols and amines. Model substrates are released in quantitative yield along with well-defined, colorless hydroquinone byproducts. Substituent modifications of the quinone core allow absorption from 400 to 600 nm.
منابع مشابه
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عنوان ژورنال:
- Journal of the American Chemical Society
دوره 139 13 شماره
صفحات -
تاریخ انتشار 2017